A magnetic resonance spectroscopic imaging (MRSI) system, comprising:
- a sample that comprises a first set of two or more chemicals, a set of chemicals to be filtered out and a second set of chemicals;
- a magnet that applies a B0 field to the first set of chemicals and the set of chemicals to be filtered out;
- an excitation/detection component that excites the first set of at least two chemicals into a first set of multiple-quantum (MQ) states into different chemical-specific MQ coherence transfer pathways of two or more chemicals, wherein the excitation/detection component applies a plurality of multiple-quantum coherence (MQC) selection gradient pulses, wherein the plurality of MQC selection gradient pulses suppress signals from a set of chemicals to be filtered out, refocuses the signals of two or more chemicals, and wherein the excitation/detection component acquires signals from the first set of at least two chemicals during a first acquisition period and wherein the excitation/detection component excites the second set of chemicals into one or more spin echo pathways, and wherein the excitation/detection component acquires signals from the second set of chemicals during the first acquisition period.