Automated system for handling components of a chromatographic system
AssigneeProxeon Biosystems A/S
InventorSoeren Theodorsen
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Abstract
An automated system for handling components of a chromatographic system, comprising: one or more trap columns each having sorbent material therein; a robotic system for moving a trap column from a storage position to an operating position where the trap column is connected in a liquid pathway along which solvent is flowed in operation to a liquid chromatography (LC) column; and an optical sensor for sensing one or more parameters of the trap column. Sensed parameters can include: a presence or absence of a trap column in the operating position, a position or orientation of the trap column, a fluid level in the trap column, the presence and position of a sorbent material in the trap column, the condition of the trap column and/or whether the trap column is new or used.
Claims18
An automated system for handling components of a chromatographic system, comprising:
- a trap column having sorbent material therein;
- a robotic system for moving the trap column from a storage position to an operating position where the trap column is connected in a liquid pathway along which solvent is flowed in operation to a liquid chromatography (LC) column;
- and
- an optical sensor for sensing one or more parameters of the trap column
- wherein the optical sensor comprises a light source and an optical detector located on opposite sides of the trap column;
- and
- wherein the optical sensor can detect light transmitted through the trap column.
A method of automatically handling components of a chromatographic system, comprising:
- using a robotic system to move a trap column having sorbent material therein from a storage position to an operating position where the trap column is connected in a liquid pathway along which solvent is flowed in operation to a liquid chromatography (LC) column;
- and
- sensing one or more parameters of the trap column using an optical sensor
- wherein the optical sensor comprises a light source and an optical detector located on opposite sides of the trap column;
- and
- wherein the optical sensor can detect light transmitted through the trap column.
Dependencies are inferred from the claim text.