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US 9,285,336 B2Granted
Sensing platform for quantum transduction of chemical information
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorChaitanya Gupta
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Abstract
A system for determining chemistry of a molecule in a high background interfering liquid environment by application of an electronic signal at a biased metal-electrolyte interface is disclosed. One or more of a resonant exchange of energy between one or more electrons exchanged by the metal and the electrolyte and vibrating bonds of a molecular analyte, for example, may be sensed by measuring small signal conductivity of an electrochemical interface.
Claims20
A system for sensing chemical information, the system comprising:
- a fluidic system, comprising:
- a sample acquisition zone;
- a filtration module coupled to the sample acquisition zone;
- an immunoseparation module coupled to the filtration module;
- a tapered micro-chromatogram coupled to the immunoseparation module;
- and
- an adsorption pad coupled to the tapered micro-chromatogram;
- and
- a quantum tunneling biosensor interface coupled to the adsorption pad, the quantum tunneling biosensor interface comprising:
- a transducing electrode array comprising dielectric thin films deposited on an electrode array;
- and
- sensor interface circuitry coupled to the transducing electrode array.
9 more elements
A system, comprising:
- a quantum tunneling biosensor interface, comprising:
- a transducing electrode array comprising dielectric thin films, the dielectric thin films being layered on a metal electrode array, the metal electrode array being mounted on a silicon die;
- sensor interface circuitry coupled to the transducing electrode array;
- and
- a voltage source to apply a voltage bias across the transducing electrode array to produce a weakly-coupled non-adiabatic electron flux.
2 more elements
A system, comprising:
- a quantum tunneling biosensor interface, comprising:
- a transducing electrode sensor array comprising at least one dielectric thin film layered on an electrode array;
- and
- sensor interface circuitry coupled to the transducing electrode sensor array;
- and
- a fluidic module, comprising:
- a sample acquisition zone;
- an immunoseparation module in fluid communication with the sample acquisition zone;
- and
- a tapered micro-chromatograph in fluid communication with the immunoseparation module and the quantum tunneling biosensor interface.
7 more elements
Dependencies are inferred from the claim text.