Calorimetric microfluidic sensor
AssigneeMarquette University
InventorsChung Hoon Lee, Benyamin Davaji
Life of this patent
Estimating the term…
Abstract
A microfluidic sensor includes a microchannel that includes a reaction site with a reagent and a sample inlet. A liquid substance is received at the sample inlet and travels by capillary action to the reaction site. A temperature sensor measures a temperature as a result of a reaction between the reagent and a chemical in the liquid substance. A controller is communicatively connected to the temperature sensor, receives the temperature measured by the temperature sensor, and derives a concentration of the chemical in the liquid substance from the temperature.
Claims20
A microfluidic sensor, the microfluidic sensor comprising:
- a microchannel constructed of paper that comprises a reaction site that comprises a reagent and a sample inlet, wherein the microchannel is configured to receive a liquid substance comprising a chemical at the sample inlet that travels by capillary action to the reaction site;
- a temperature sensor located proximal the reaction site of the microchannel and configured to measure a temperature as a result of a reaction between the reagent and the chemical in the liquid substance;
- and
- a controller communicatively connected to the temperature sensor, the controller receives the temperature measured by the temperature sensor and derives a concentration of the chemical in the liquid substance from the temperature.
A microfluidic sensor system comprising:
- at least one microfluidic sensor, comprising:
- a microchannel constructed of paper that comprises a reaction site that comprises a reagent and a sample inlet, wherein the microchannel is configured to receive a liquid substance comprising a chemical at the sample inlet that travels by capillary action to the reaction site;
- and
- a temperature sensor located proximal the reaction site of the microchannel and configured to measure a temperature as a result of a reaction between the reagent and the chemical in the liquid substance;
- a controller communicatively connected to the at least one microfluidic sensor, the controller receives the temperature measured by the temperature sensor of at least one microfluidic sensor and derives a concentration of the chemical in the liquid substance from the temperature;
- and
- a graphical display operated by the controller to present the derived concentration of the chemical in the liquid substance.
A microfluidic sensor, the microfluidic sensor comprising:
- a microchannel that comprises a reaction site on a first finger, the reaction site comprises a reagent, a sample inlet, and a second finger wherein the microchannel is configured to receive a liquid substance comprising a chemical at the sample inlet that travels by capillary action to the reaction site;
- a first temperature sensor located proximal to the reaction site on the first finger of the microchannel and configured to measure a first temperature as a result of a reaction between the reagent and the chemical in the liquid substance;
- a second temperature sensor located proximal to the second finger of the microchannel and configured to measure a second temperature;
- and
- a controller communicatively connected to the first temperature sensor and the second temperature sensor, the controller receives the first temperature and the second temperature and the controller derives a concentration of the chemical in the liquid substance from a differential between the first temperature and the second temperature.
Dependencies are inferred from the claim text.