Disposable heat exchanger assembly for sterile and aseptic biotechnology and pharmaceutical manufacturing applications

A heat exchanger assembly for controlling the temperature of fluid flowing through the assembly, said heat exchanger assembly comprising:

• a plurality of plate members each comprised of spaced apart plates that define a flow path therebetween;
• a plurality of bags through which a fluid to be processed passes;
• said bags being disposed between adjacent plate members;
• said plate members interconnected so that heating/cooling fluid flowing therethrough couples from plate member to plate member;
• said bags interconnected so that media to be heated/cooled flowing therethrough couples from bag to bag, wherein said media in said flow path of said bag assembly is fully contained within said bag assembly such that it does not contact said plate members;
• said plate members interconnected so that the flow therethrough is in a serpentine flow path;
• said bags interconnected so that the flow therethrough is in a serpentine flow path;
• the direction of flow in the respective plate members and bags being reversed from each other.