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US 9,284,532 B2Granted
Mammalian cells for propagating virus
AssigneeIntervet Inc.
InventorsLars Guelen, Carla Christina Schrier
Life of this patent
Estimating the term…
Abstract
The present invention relates to mammalian cells capable of propagating Arterivirus, to such cells infected with Arterivirus, to cell cultures comprising such cells and to methods for the propagation of an Arterivirus in such cells.
Claims17
A mammalian cell that is deficient in its IFN-β production due to a deliberate blocking of IFN-β production in the cell;
- wherein when the cell is infected with a porcine reproductive and respiratory syndrome virus (PRRSV) said deliberate blocking is additional to the blocking effect of the PRRSV;
- and
- wherein the cell is capable of propagating the PRRSV.
Dependencies are inferred from the claim text.