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US 9,284,520 B2Granted
Instruments for biological sample preparation devices
AssigneeCalifornia Institute of Technology
InventorsImran R. Malik, Erika F. Garcia, Xiomara Linnette Madero, Axel Scherer
Life of this patent
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Abstract
Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
Claims12
An instrument comprising:
- a recess;
- a sample preparation device;
- a supporting element, configured to attach to the sample preparation device to secure the sample preparation device in the recess inside the instrument;
- at least one motorized actuator, configured to actuate plungers of the sample preparation device that are arranged in a circular pattern, wherein the at least one motorized actuator comprises
- a motor comprising a rotating rod having a rotating axis,
- a fixed plate attached to the rotating axis, and
- a linear actuator having a first end and a second end, wherein the first end is attached to the fixed plate, and the second end is attached to an actuator rod, the actuator rod having an axis parallel to the rotating axis of the motor, and wherein the actuator rod is configured to operate the plungers;
- a controlling interface, configured to accept input from a user and operate the at least one motorized actuator based on the input from the user;
- and
- a housing structure, containing the recess, the supporting element, the at least one motorized actuator, and the controlling interface.
7 more elements
Dependencies are inferred from the claim text.