Back to results
US 9,284,363 B2Granted
System and method for controlling G-protein coupled receptor pathways
AssigneeCase Western Reserve University
InventorsStefan Herlitze, Lynn Landmesser
Life of this patent
Estimating the term…
Abstract
A light-sensitive G-protein coupled receptor includes a light sensitive extracellular domain and a heterologous intracellular domain capable of modulating an intracellular signaling pathway.
Claims7
A mammalian cell comprising:
- a first light-sensitive G-protein coupled receptor, the first GPCR being activated by light having a first wavelength and once activated affecting a first cell signaling pathway,
- a second light-sensitive G-protein coupled receptor, the second GPCR being activated by light having a second wavelength and once activated affecting a second signaling pathway, the second wavelength being different than the first wavelength and the second signaling pathway being different from the first signaling pathway.
Dependencies are inferred from the claim text.