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US 9,284,357 B2Granted
AAV's and uses thereof
AssigneeUniversity of Massachusetts
InventorsGuangping Gao, Terence Flotte, Jun Xie
Life of this patent
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Abstract
The invention in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the invention relates to gene transfer methods using the recombinant adeno-associate viruses. In some aspects, the invention relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.
Claims5
A composition comprising an isolated adeno-associated virus (AAV) vector wherein the isolated adeno-associated virus (AAV) vector comprises
- (i) the isolated adeno-associated virus (AAV) capsid protein of the amino acid sequence SEQ ID NO:
- 91;
- and
- (ii) a nucleic acid encoding a heterologous transgene.
1 more element
Dependencies are inferred from the claim text.