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US 9,284,341 B2Granted
Rapidly dissolving pharmaceutical composition
AssigneeUniversity of the Witwatersrand
InventorsPradeep Kumar, Viness Pillay, Yahya Essop Choonara
Life of this patent
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Abstract
The present invention relates to a pharmaceutical dosage form which may comprise carbamoyl glycinated chitosan, and particularly it relates to a pharmaceutical dosage form comprising the novel polymer in a lyophilized polymeric wafer form which shows rapid disintegration and dissolution characteristics in use.
Claims19
A compound of the Formula (I):
A pharmaceutical dosage form comprising:
- a compound of the formula (I)
- Wherein the compound of the formula (I) is termed carbamoyl glycinated chitosan (CmGC);
- a soluble matrix polymer in the form of hydroxypropyl cellulose (HPC);
- an ester containing derivative of an acrylic polymer in the form of sodium polyacrylate;
- an anti-collapsing agent in the form of diglycine;
- and
- a filter substance in the form of maltodextrin.
4 more elements
A pharmaceutical dosage form comprising:
- a compound of Formula (I), (carbamoyl glycinated-chitosan);
- a soluble matrix forming polymer in the form of hydroxypropyl cellulose (HPC);
- an ester containing derivative of an acrylic polymer in the form of sodium polyacrylate;
- an anti-collapsing agent in the form of diglycine;
- and
- a filler substance in the form of maltodextrin.
3 more elements
Dependencies are inferred from the claim text.