Tight connection and tight transfer between two housings in view of an aseptic transfer therebetween

Sealed junction device between a first chamber (1) and a second chamber that are isolated from the external environment,

• the first chamber (1) comprising:
• a structure that includes a first wall (3) that borders a first inside space (1a) and has a first opening (4) that is bordered by a first annular flange (5);
• and
• a first door (6) that is supported by the structure and that includes a panel (6v) that is arranged and mounted so as to be able to be moved to be either in the closed state where it works with the first annular flange (5) by closing the first opening (4) or in the open state where it is detached from the first annular flange (5) and placed in the first inside space (1a) by opening the first opening (4);
• the second chamber (2) comprising:
• a second wall (7) that is equipped with a second opening (8) that is bordered by a second annular flange (9);
• and
• a second door (10) that has a second panel (10v) that is mounted to move between a closed state and an open state, where, respectively, the second panel (10v) closes or opens the second opening (8);
• wherein the first annular flange (5) and the second annular flange (9) are complementary and adapted to be held in a removable way, flattened against one another by their end surfaces (5a, 9a);
• wherein the first panel (6v) and the second panel (10v) are complementary and adapted to be flattened against one another in a removable way, hermetically sealed, by their outside surfaces (6a, 10a);
• wherein the device comprises movement actuation means (11b) for moving the first panel (6v) between its closed and open states, and monitoring means (11c) for monitoring the movement actuation means;
• wherein when the first door (6) and the second door (10), respectively their panels (6v and 10v), are in the open state, the first chamber (1) and the second chamber (2) are in communication with one another via their respective openings (4, 8) in the open state, with a communication space (13) that includes an entrance/exit space (13a) in the first chamber (1) and an entrance/exit space in the second chamber (2) being made between the two chambers (1, 2) that make possible passage of contents from one said entrance/exit space to the other;
• wherein an inside critical annular line (LCi) of contamination risk exists on the first panel (6v) of the first door (6), and an outside critical annular line (LCe) of contamination risk exists on the second annular flange (9);
• and
• wherein the device further comprises protective means for reducing a risk of contamination for the outside critical line, the protective means comprising at least one of a first member (25) surrounding the first door (6) and a second member (26) structurally integrated into the second flange (9) that are adapted, when the first door (6) and the second door (10), respectively their panels (6v and 10v), are in the open state, to form a separation between the communication space (13) and the inside critical annular line (LCi) and the outside critical annular line (LCe).