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US 9,283,280 B2Granted
Compositions for drug administration
AssigneeAegis Therapeutics, LLC
InventorEdward T. Maggio
Life of this patent
Estimating the term…
Abstract
The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject, as well as compositions and methods for providing migraine pain relief. The compositions include at least one alkyl glycoside and at least one therapeutic agent, such as a 5-HT receptor agonist, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms.
Claims20
A composition comprising:
- a) a therapeutically effective amount of a 5-HT receptor agonist, the 5-HT agonist being sumatriptan, naratriptan, rizatriptan, eletriptan, frovatriptan, almotriptan, zolmitriptan, salt thereof, or combination thereof;
- and
- b) an alkylsaccharide having an alkyl chain including between 10 to 16 carbons, wherein the composition is formulated for intranasal administration, exhibits a Tmax of less than about 20 minutes, and exhibits a Cmax greater than 15 ng/mL.
Dependencies are inferred from the claim text.