Compositions for treating biofilms and methods for using same
AssigneePluroGen Therapeutics, Inc.
InventorsGeorge Rodeheaver, Adam Katz
Life of this patent
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Abstract
Compositions containing a surface active agent and a sub-lethal amount of an antimicrobial agent and methods for using such compositions are provided herein.
Claims26
A method for treating a wound comprising contacting the wound with a composition containing about 30 w/w % to about 80 w/w % of a surface active agent selected from the group consisting of poloxamer 127, poloxamer 188, poloxamer 237, poloxamer 335, poloxamer 407, and combinations thereof and about 1% or less by weight of the composition of an antimicrobial agent.
A method for treating a diabetic ulcer comprising contacting the diabetic ulcer with a composition containing about 30 w/w % to about 80 w/w % of a surface active agent selected from the group consisting of poloxamer 127, poloxamer 188, poloxamer 237, poloxamer 335, poloxamer 407, and combinations thereof and less than 1% by weight of the composition of an antimicrobial agent.
A composition comprising:
- about 30 w/w % to about 80 w/w % of a surface active agent selected from the group consisting of poloxamer 127, poloxamer 188, poloxamer 237, poloxamer 335, poloxamer 407, and combinations thereof;
- and
- less than about 1% by weight of the composition of an antimicrobial agent.
A composition comprising:
- about 30 w/w % to about 80 w/w % poloxamer;
- and
- less than about 1% by weight of the composition nitrofurantoin.
A composition comprising:
- about 30 w/w % to about 80 w/w % poloxamer;
- and
- less than about 1% by weight of the composition silver sulfadiazine.
A composition comprising:
- about 30 w/w % to about 80 w/w % poloxamer;
- less than about 1% by weight of the composition polymixin;
- and
- less than about 1% by weight of the composition nitrofurantoin.
A composition comprising:
- about 30 w/w % to about 80 w/w % poloxamer;
- less than about 1% by weight of the composition nanocrystalline silver.
A composition comprising:
- about 30 w/w % to about 80 w/w % poloxamer;
- less than about 1% by weight of the composition ionic silver.
Dependencies are inferred from the claim text.