Lactic acid bacterium having high oxalic acid decomposition ability
AssigneeMeiji Co., Ltd.
InventorsDaisuke Ochi, Hiroshi Tsuboi
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Abstract
The present invention provides lactic acid bacteria having oxalic acid-degrading activity several times higher than those of conventionally known lactic acid bacteria having an oxalic acid-degrading activity, and uses thereof. Lactic acid bacteria capable of degrading a large amount of oxalic acid were screened from 132 strains of Lactobacillus lactic acid bacteria that have been independently isolated from feces and gastric juices of human adults. As a result, lactic acid bacteria having an oxalic acid degradation rate of 50% or more when cultured at 37° C. for 72 hours in a culture medium containing 10 mM oxalic acid at pH 6.5 at the start of culture were discovered.
Claims2
A composition comprising a lactic acid bacterium belonging to the genus Lactobacillus in an amount effective for treating renal/urinary calculus and a component selected from the group consisting of light anhydrous silicic acid, lactose, crystalline cellulose, mannitol, starch, calcium carmellose, sodium carmellose, hydroxypropylcellulose, hydroxypropylmethylcellulose, polyvinylacetal diethylaminoacetate, polyvinylpyrrolidone, gelatin, polyoxyethylene hydrogenated castor oil 60, sucrose, carboxymethylcellulose, and corn starch, wherein the lactic acid bacterium is the Lactobacillus gasseri OLL2727 strain, deposited under Accession No. FERM BP-11004.
Dependencies are inferred from the claim text.