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AssigneeCatholic University Industry Academic Cooperation Foundation
InventorsMi-La Cho, Seon-Yeong Lee, Young-Mee Moon, Jun-Geol Ryu, Yang-Mi Her, Hye-Jwa Oh
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The present invention relates to a composition containing PIAS3 as an active ingredient for the prevention or treatment of cancer or immune disease. More specifically, the present invention relates to a composition containing the PIAS3 gene or an expressing protein thereof as an active ingredient for the prevention or treatment of cancer or immune disease, to an immunosuppressant composition, to a method for reducing or inhibiting undifferentiated T cells into Th17 cells using the PIAS3 gene or an expressing protein thereof, and to a method for activating regulatory T cells.
A method of treating Behcet's disease or arthritis comprising administering to a subject in need thereof a pharmaceutical composition comprising an expression vector comprising a nucleic acid encoding PIAS3 (protein inhibitor of activated STAT3) as an active ingredient.
Dependencies are inferred from the claim text.