Solid, orally administrable pharmaceutical composition
AssigneeBayer Intellectual Property GmbH
InventorKlaus Benke
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Abstract
The present invention relates to a process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, and its use for the prophylaxis and/or treatment of diseases.
Claims17
A process for the preparation of a solid, orally administrable pharmaceutical composition comprising an active compound (I) that is 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, comprising the following steps:
- (a) first preparing granules comprising the active compound (I) in hydrophilized form using fluidized bed granulation for moist granulation;
- (b) and converting the granules into the pharmaceutical composition, if appropriate with addition of pharmaceutically suitable additives.
A solid, orally administrable pharmaceutical composition comprising an active compound (I) that is 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form prepared by a process comprising the following steps:
- (a) first preparing granules comprising the active compound (I) in hydrophilized form using fluidized bed granulation for moist granulation;
- (b) and converting the granules into the pharmaceutical composition, if appropriate with addition of pharmaceutically suitable additives.
Dependencies are inferred from the claim text.