Process for the preparation of a solid, orally administrable pharmaceutical composition
AssigneeBayer Intellectual Property GmbH
InventorKlaus Benke
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Abstract
A process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide comprising preparing granules in hydrophilized form using fluidized bed granulation for moist granulation, adding additives, compressing to form a tablet, and coating the tablet.
Claims2
A process for the preparation of a solid, orally administrable pharmaceutical tablet comprising an active compound (I) that is 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, comprising the following steps:
- (a) preparing granules comprising the active compound (I) in hydrophilized form using fluidized bed granulation for moist granulation;
- (b) adding at least one pharmaceutically suitable additive to the granules and compressing to form a tablet;
- and
- (c) coating to form the pharmaceutical tablet.
Dependencies are inferred from the claim text.