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US 9,283,205 B2Granted
Method for extracting treatment ingredients for gastrointestinal diseases from bark of liriodendron tulipifera
AssigneeCho Dang Pharm. Co., Ltd.
InventorNak Doo Kim
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Abstract
The present invention relates to a method for extracting treatment ingredients for gastrointestinal diseases from the bark of Liriodendron tulipifera, the treatment ingredients containing epitulipinolide and costunolide as active ingredients, and to a therapeutic agent for gastrointestinal diseases, containing epitulipinolide and costunolide extracted using said method.
Claims2
A process for preparing an extract from the bark of Liriodendron tulipifera comprising the steps of:
- a) mixing 1 weight part of chopped and dried bark of Liriodendron tulipifera with 2 to 20 weights part of ethyl acetate or dichloromethane to form a mixture;
- and
- b) extracting and concentrating said mixture for 1 to 4 days at a temperature of 15° C. to 50° C. to form the extract of the bark of Liriodendron tulipifera,
- wherein said extract comprises 0.1 to 10 weight of epitulipinolide and costunolide, and
- wherein said extraction is made by at least one technique selected from the group consisting of:
- enfleurage, percolation, ultra sonic, maceration and reflux.
3 more elements
Dependencies are inferred from the claim text.