Benzimidazole anthelmintic compositions
AssigneeZoetis Services LLC
InventorsRobert Bruce Albright, Moses Collumbus Lawrence, Shobhan Shashikant Sabnis, Sivaja Ranjan
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Abstract
The present invention provides a veterinary anthelmintic composition that includes: at least 10% w/v of a benzimidazole anthlemintic; and b) a water-immiscible solvent system, which comprises a lactone solvent, an essential oil, and surfactant.
Claims12
A self-emulsifying, pour-on, veterinary anthelmintic composition comprising:
- a) 15 to 25% w/v of triclabendazole;
- and b) a water-immiscible solvent system, which comprises a lactone solvent in an amount of about 10% to about 40% w/v, wherein said lactone solvent is γ-hexalactone;
- an essential oil in an amount of about 29% w/v, and surfactant in an amount of about 30% to about 60% w/v, wherein the surfactant is selected from PEG-8 caprylic/capric glycerides or PEG-6 caprylic/capric glycerides.
A self-emulsifying, pour-on, veterinary anthelmintic composition, comprising:
- about 15% to about 25% w/v of triclabendazole;
- and b) a water immiscible solvent system, which comprises γ-hexalactone in an amount of about 10% to about 40% w/v, 1,8-cineole in an amount of about 10% to about 35% w/v, and PEG-8 caprylic/capric glycerides in an amount of about 30% to about 60% w/v.
A method of treating parasites in a homeothermic animal, said method comprising administering to said animal a self-emulsifying, pour-on, veterinary anthelmintic composition comprising:
- a) about 15% to about 25% w/v of triclabendazole, and b) a water-immiscible solvent system, which comprises γ-hexalactone in an amount of about 10% to about 40% w/v, about 10% to about 35% w/v of the essential oil, 1,8-cineole, and surfactant in an amount of about 30% to about 60% w/v, wherein the surfactant is PEG-8 caprylic/capric glycerides or PEG-6 caprylic/capric glycerides, and wherein said composition further comprises moxidexctin in an amount of about 0.01 to about 2% w/v.
A self-emulsifying, pour-on, veterinary anthelmintic composition comprising:
- a) 20% triclabendazole, and b) a water-immiscible solvent system, which comprises a γ-hexalactone in an amount of about 14% w/v, 1,8-cineole in an amount of about 29% w/v, and PEG-8 caprylic/caprylate as a surfactant in an amount of about 36% w/v.
Dependencies are inferred from the claim text.