Methods and compositions for treatment of epithelial wounds
OwnerIan S. Zagon, Patricia J. McLaughlin +1inventors
InventorsIan S. Zagon, Patricia J. McLaughlin, Joseph W. Sassani
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Abstract
This invention relates to treatment of epithelial wounds. In particular, the invention relates to methods and formulations for treating epithelial wounds based on application of an opioid antagonist such as naltrexone.
Claims27
A method of treating an epidermal or dermal wound in a subject, comprising administration of an effective amount of an opioid antagonist to the wounded area of the subject, wherein said subject is diabetic.
A method of treating an epidermal or dermal wound in a subject, comprising administration of an effective amount of an opioid antagonist to the wounded area of the subject, wherein the opioid growth factor receptor (OGFr) is present on epidermal or dermal cells adjacent to said wound.
A method of treating an epidermal or dermal wound in a subject, comprising administration of an effective amount of an opioid antagonist to the wounded area of the subject, wherein administration of said opioid antagonist aids in wound contraction.
Dependencies are inferred from the claim text.