Plaque stabilization using cryoenergy
AssigneeCryotherapeutics GmbH
InventorsMaurice Buchbinder, Randell Louis Werneth, Yiannakis Petrou Yianni, J. Christopher Flaherty, Daniel Nahon, Domenic Santoianni
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Abstract
There is provided a method of supplying cryoenergy to a plaque within a blood vessel. The method comprises expanding an expandable membrane of a catheter apparatus with a pressure of less than 5 ATM (507 kPa), the catheter apparatus having been placed in thermal contact with the plaque within the blood vessel. The method also comprises establishing a temperature of between +15° C. (288K) and −35° C. (238K) at an interface of the expandable membrane and the blood vessel. A system and catheter apparatus are also provided.
Claims23
A method of supplying cryoenergy to a plaque within a blood vessel, comprising:
- expanding a single expandable membrane of a catheter apparatus using a liquid to less than 5 ATM (507 kPa), the catheter apparatus having been placed in thermal contact with the plaque within the blood vessel;
- and,
- establishing a temperature of between +15° C. (288K) and −35° C. (238K) at an interface of the expandable membrane and the blood vessel.
A system comprising:
- a catheter apparatus, the catheter apparatus having a single expandable membrane;
- a pressure control system configured to regulate the expansion of the expandable membrane using a liquid such that the expandable membrane is expanded with a pressure of less than 5 ATM (507 kPa);
- and,
- a cooling element configured to establish a temperature of between +15° C. (288K) and −35° C. (238K) at an interface between the expandable membrane and a blood vessel when the catheter apparatus has been placed in the blood vessel;
- and
- a temperature control system configured to monitor temperature at the interface and adjust the cooling element to maintain the interface temperature between +15° C. (288K) and −35° C. (238K).
Dependencies are inferred from the claim text.