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US 9,282,923 B2Granted
Fluorochrome material and method for using the same
AssigneesIHI Corporation, Yoshihiro Ishikawa
InventorsYoshihiro Ishikawa, Haruki Eguchi
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Abstract
It is an object of the present invention to extend the usefulness of an iron-salen complex. The present invention is a new fluorochrome material containing Chemical Formula (I) below. However, M is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd.
Claims4
A method comprising:
- administering to an individual a fluorochrome material containing a metal-salen complex represented by Chemical Formula (I);
- N,N′-Bis(salicylidene)ethylenediamine metal,
- wherein M is Fe, Cr, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd, and the metal-salen complex is in the form of a particle having a particle diameter in the range of 2 to 60 μm;
- externally applying a magnetic field to the individual to guide the fluorochrome material to a target area;
- applying external light to the target area, thereby causing the fluorochrome material in the target area to luminesce, with a peak luminous wavelength of the metal-salen complex represented by Chemical Formula (I) around 380 nm;
- confirming luminescence in the target area visually;
- and
- removing luminescent target area tissue.
5 more elements
Dependencies are inferred from the claim text.