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US 9,281,174 B2Granted
System and method for rapid evaporative ionization of liquid phase samples
AssigneeMicromass UK Limited
InventorZoltan Takats
Life of this patent
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Abstract
According to some embodiments, systems and methods for rapid evaporation of liquid phase samples are provided. The method includes directing liquid samples to a thermal evaporation ionizing device, thermally evaporating the liquid samples to create gaseous molecular ions, and directing the gaseous molecular ions to an ion analyzer to analyze and provide information regarding the chemical composition of the liquid samples.
Claims35
A method for analyzing liquid phase samples, comprising
- guiding a liquid sample to an ionizing device;
- and
- thermally evaporating the liquid sample with the ionizing device at a rate sufficient to convert one or more molecular components of the liquid sample to one or more gaseous ions and neutral particles.
A system for analyzing liquid phase samples, comprising
- a conduit configured to guide a liquid sample therethrough;
- a thermal evaporation ionizing device configured to receive the liquid sample from the conduit, the ionizing device configured to thermally evaporate the liquid sample at a rate sufficient to convert one or more molecular components of the liquid sample into one or more gaseous ions and neutral particles;
- and
- a transport device configured to receive the one or more gaseous ions from the ionizing device.
1 more element
A system for analyzing liquid phase samples, comprising
- a microtiter plate comprising one or more microwells configured to receive a liquid sample therein;
- a thermal evaporation ionizing device comprising a pair of electrodes defining a gap therebetween, at least a portion of the electrodes configured to be submerged in the liquid sample and configured to thermally evaporate the liquid sample at a rate sufficient to convert one or more molecular components of the liquid sample into one or more gaseous ions and neutral particles;
- and
- a conduit configured to receive the one or more gaseous ions from the ionizing device.
1 more element
Dependencies are inferred from the claim text.