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US 9,278,999 B2Granted
Influenza C virus and vaccine
AssigneeNewport Laboratories, Inc.
InventorsRandy R. Simonson, Benjamin M. Hause, Emily A. Collin
Life of this patent
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AssigneeNewport Laboratories, Inc.
InventorsRandy R. Simonson, Benjamin M. Hause, Emily A. Collin
Estimating the term…
A novel influenza C virus with only low homology to any influenza C virus previously characterized. Challenge studies show that the virus can infect pigs and be transmitted between pigs. Additionally, influenza C is commonly thought of as a human pathogen and serological studies have been performed, looking at the incidence of antibodies against this virus in both pigs and humans. Approximately 10% of pigs and 30% of humans have antibodies to this virus. Additional experimental data show that the virus can infect and transmit in ferrets (a surrogate for human infection studies). In a third aspect, the present invention is the partial genome of this novel influenza C virus. In another aspect, the present invention is a method of detection in animals of this novel influenza C virus.
A vaccine for protecting a mammal against infection by an influenza C virus, comprising an acceptable carrier, an immunologically effective amount of a binary ethyleneimine-inactivated swine influenza C virus and an oil in water adjuvant;
Dependencies are inferred from the claim text.