4-dedimethylamino tetracycline compounds
AssigneeParatek Pharmaceuticals, Inc.
InventorsMark L. Nelson, Kwasi Ohemeng
Life of this patent
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Abstract
The present invention pertains, at least in part, to novel substituted 4-dedimethylamino tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Claims14
A method for ameliorating rheumatoid arthritis in a subject in need thereof, the method comprising administering to said subject an effective amount of a tetracycline compound of the following structural formula:
- or a pharmaceutically acceptable salt thereof, such that said rheumatoid arthritis in said subject is ameliorated.
A method for ameliorating rheumatoid arthritis in a subject in need thereof, the method comprising administering to said subject an effective amount of a pharmaceutical composition comprising a tetracycline compound of the following structural formula:
- or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, such that said rheumatoid arthritis in said subject is ameliorated.
Dependencies are inferred from the claim text.