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US 9,266,734 B2Granted
Chlorite formulations and methods of preparation and use thereof
AssigneeNeuraltus Pharmaceuticals, Inc.
InventorsWilliam Boulanger, Arasteh Ari Azhir
Life of this patent
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Abstract
Described herein are chlorite formulations having a pH between about 7 and about 8.5, wherein the chlorite formulations are substantially free of deleterious non-chlorite components. Described herein are chlorite formulations, including pharmaceutical formulations, which are formulated for systemic, parenteral, or intravenous administration. Described herein are methods of preparing and methods of using the chlorite formulations described herein.
Claims15
A kit for treatment of neurodegenerative disease in a patient in need thereof comprising
- (i) one or more unit doses of a pharmaceutically acceptable salt of chlorite;
- (ii) a physiologically compatible buffer comprising phosphate in an amount sufficient to result in a pH between about 7 and about 9 when combined with said one or more unit doses;
- (iii) physiological saline solution;
- and
- (iv) instructions for treatment of neurodegenerative disease by intravenous administration of said one or more unit doses of a pharmaceutically acceptable salt of chlorite and said pH adjusting agent;
- wherein said chlorite is purified to greater than about 95% chlorite ions to non-chlorite ions.
3 more elements
Dependencies are inferred from the claim text.