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US 9,249,191 B2Granted
Virus like particle composition
AssigneeVLP Therapeutics, LLC
InventorsRyuji Ueno, Wataru Akahata
Life of this patent
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Abstract
The present invention provides a particle comprising a polypeptide and at least one antigen, and a composition comprising thereof.
Claims14
A Chikungunya virus (CHIKV) or Venezuelan equine encephalitis virus (VEEV) virus-like particle, wherein said virus-like particle contains at least one antigen inserted into an E2 envelope protein to form a fusion protein,
- wherein the at least one antigen is inserted within a CHIKV E2 envelope protein within a region that corresponds in position to residues 509-512, residues 519-520, or residues 529-533 of SEQ ID NO:
- 1 or 2;
- or wherein the at least one antigen is inserted within a VEEV E2 envelope protein within a region that corresponds in position to residues 515-520, or residues 536-539 of SEQ ID NO:
- 3.
1 more element
Dependencies are inferred from the claim text.