Use of M-CSF antibodies in the treatment of osteoarthritis or pain
AssigneesThe University of Melbourne, Morpho Sys AG
InventorsStefan Steidl, John Allan Hamilton, Andrew David Cook
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Abstract
The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA) and/or pain. In accordance with the present invention, an antagonist of c-Fms is effective in the treatment of osteoarthritis and/or pain. An antagonist of M-CSF includes, but is not limited to, an antibody that is specific for M-CSF, IL-34 or c-Fms.
Claims4
A method for the treatment of pain in a subject, comprising administering to the subject an antibody or antigen binding fragment thereof specific for M-CSF, wherein the pain is post-surgical pain or bone cancer pain.
Dependencies are inferred from the claim text.