Infectious Schmallenberg virus from cloned CDNAS and uses thereof
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsIlona Reimann, Martin Beer, Kerstin Wernike
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Abstract
The present invention belongs to the field of animal health and relates to a nucleic acid sequence which comprises the complete genome of an infectious Schmallenberg virus (SBV) useful for studying viremia and diseases caused by SBV in ruminants, and in the development of vaccines, therapeutics and diagnostics for the prophylaxis, treatment and diagnosis of viremia and diseases caused by SBV.
Claims16
A plasmid or cDNA construct encoding a complete antigenomic RNA sequence of a M segment of a Schmallenberg virus (SBV) vRNA genome comprising the cDNA sequence SEQ ID NO:2.
A plasmid or cDNA construct encoding a complete antigenomic RNA sequence of an S segment of a Schmallenberg virus (SBV) vRNA genome comprising the cDNA sequence SEQ ID NO:7.
A plasmid or cDNA construct encoding a complete antigenomic RNA sequence of a L segment of a Schmallenberg virus (SBV) vRNA genome, comprising inserted material the cDNA sequence SEQ ID NO:3.
Dependencies are inferred from the claim text.