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US 9,238,689 B2Granted
Antibodies that are cross-reactive for macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT)
AssigneeMorpho Sys AG
InventorsSwen Zierow, Juergen Klattig
Life of this patent
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Abstract
The present disclosure relates to antigen-binding moieties that specifically bind to MIF and D-DT and compositions and methods of use thereof.
Claims34
An isolated antigen-binding moiety, wherein the antigen-binding moiety specifically binds human MIF and human D-DT,
- wherein the antigen-binding moiety recognizes an epitope of MIF,
- wherein a similar epitope is present in D-DT and
- wherein said isolated antigen-binding moiety recognizes both epitopes,
- said epitopes in MIF and D-DT comprise an amino acid shown in FIG. 1 that
- is identical in human MIF and human D-DT.
2 more elements
Dependencies are inferred from the claim text.