Cephalosporin having catechol group

A compound of the formula:

• wherein,
• X is N, CH or C—Cl;
• T is S, S═O, CH2 or O;
• A is lower alkylene, lower alkenylene or lower alkynylene;
• G is optionally present, and when present is, —CH2—CH(CH3)—, —CH2—CH(iPr)—, lower alkylene optionally substituted with a carbocyclic group, lower alkenylene, or lower alkynylene;
• B is optionally present, and when present B is a 5- or 6-membered heterocyclic group containing at least 1 N atom(s);
• D is optionally present, and when present D is, —CO—, —O—CO—, —CO—O—, —NR7—, —NR7—CO—, —CO—NR7—, —NR7—CO—NR7—, —O—, —S—, —SO—, —SO2—NR7—, —NR7—SO2—, —CH2—NR7—CO— or —SO2—;
• E is of the formula:
• wherein R1 and R2 are each independently hydrogen, halogen, lower alkyl optionally substituted with carbamoyl, lower alkylthio, or phenyl, R11 and R12 are each independently hydrogen, lower alkyl optionally substituted with carbamoyl or carboxyl, carboxyl, or a carbamoyl, and m refers to an integer of 1 to 5;
• F is optionally present, and when present F is phenylene;
• R3 and R4 are —OR8;
• R5 and R6 each is independently hydrogen, halogen, nitrile, or —OR8;
• R7 each is independently hydrogen or lower alkyl;
• R8 each is independently hydrogen, lower alkyl, halo(lower)alkyl, lower alkylcarbonyl or carbamoyl;
• the formula:
• is an optionally substituted, saturated or unsaturated, monocyclic or condensed cyclic quaternary ammonium group containing one or more N atom(s);
• wherein the substituents are at least one selected from the group consisting of halogen, hydroxy, lower alkyl, halo(lower)alkyl, lower alkoxy, and halo(lower)alkoxy;
• the broken line represents the presence or absence of a bond between the cationic N atom and a ring-forming atom;
• provided that
• when G bonds to the cationic N atom, the broken line is absent;
• when G does not bond to the cationic N atom, the broken line represents a single bond between the cationic N atom and a neighboring atom or represents lower alkylene between the cationic N atom and a ring-forming atom other than the neighboring atom;
• and
• when G and B are not present, and D is —NH—CO— or —S—, then a group of the formula:
• is not a group of the formula:
• wherein a hydrogen atom(s) on the quaternary ring is(are) optionally substituted;
• or an ester at the carboxyl at the 7-position side chain or at the 4-position, a protected compound at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof.