Method of improving aging appearance of skin by modulation of WIPI-1
AssigneeAvon Products, Inc.
InventorsPermanan Raaj Khusial, Uma Santhanam, John W. Lyga
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Abstract
Methods of using WIPI-1 to impart anti-aging benefits to the skin and/or improve skin conditions resulting from reduced autophagy activity.
Claims1
A method for improving the aesthetic appearance of skin of a human affected by aging resulting from reduced autophagy activity within skin cells of the human comprising topically applying thereto a therapeutically effective amount of an extract of Tiliacora triandra that upregulates WIPI-1 in vitro by greater than 60% when applied to fibroblasts at a concentration of 0.1% (w/w) in a cosmetically acceptable vehicle for a time sufficient to achieve an improvement in the appearance of said skin of said human.
Dependencies are inferred from the claim text.