Back to results
US 9,234,213 B2Granted
Compositions and methods directed to CRISPR/Cas genomic engineering systems
AssigneeSystem Biosciences, LLC
InventorFangting Wu
Life of this patent
Estimating the term…
Abstract
The invention relates to engineered CRISPR/Cas9 systems for genomic modification in mammalian cells. The present specification describes the design and testing of a polynucleotide encoding the Streptococcus pyogenes (S. pyogenes) Cas9 protein, where the nucleotide sequence has been optimized for expression in mammalian cells. The specification also describes all-in-one systems for RNA-guided genome engineering in mammalian cells, including human cells.
Claims7
A polynucleotide comprising the nucleotide sequence of positions 91 through 4191 of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.