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US 9,220,761 B2Granted
Alginate and alginate lyase compositions and methods of use
AssigneeThe John Hopkins University
InventorsBradley P. Barnett, Philippe Gailloud
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Abstract
The invention features alginate and alginate lyase compositions and methods that are useful for the treatment of various conditions and diseases. The invention also provides kits and instructions for use.
Claims19
A method for dissolving a purified alginate gel crosslinked with a divalent cation in a subject, the method comprising:
- contacting in the subject the purified alginate gel crosslinked with a divalent cation with a composition comprising an alginate lyase, thereby dissolving the purified alginate gel crosslinked with a divalent cation.
A method for dissolving a purified alginate gel crosslinked with a divalent cation in a subject, the method comprising:
- contacting in the subject the purified alginate gel crosslinked with a divalent cation with a composition comprising an alginate lyase and a divalent metal chelator, thereby dissolving the purified alignate gel crosslinked with a divalent cation.
Dependencies are inferred from the claim text.