Silicone hydrogel contact lenses
AssigneeCooperVision International Holding Company, LP
InventorsYuwen Liu, Junhao Ge, Charlie Chen, Yuan Xu, Li Yao, Arthur Back, Charles A. Francis
Life of this patent
Estimating the term…
Abstract
Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one acrylate-containing siloxane monomer, at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent. The contact lenses have ophthalmically-acceptable ionoflux values and surface wettability, and can be manufactured without the use of volatile organic solvents.
Claims34
A silicone hydrogel contact lens comprising:
- a polymeric lens body that is a reaction product of a polymerizable composition comprising
- a) at least one acrylate-containing siloxane monomer represented by formula (I):
- where m is an integer from 3 to 10, n is an integer from 0 to 10, R1 is an alkyl group having 1 to 4 carbon atoms, R2 is hydrogen or a methyl group, and R3 is hydrogen or a methyl group;
- b) at least one hydrophilic vinyl-containing monomer;
- and
- c) at least one vinyl-containing cross-linking agent,
- wherein the contact lens has an ionoflux of less than 10×10−3 mm2/min;
- and
- wherein the polymerizable composition has a molar ratio of total amount of hydrophilic vinyl-containing monomer to total amount of acrylate-containing siloxane monomer of from 5:1 to 30:1, respectively.
A method of manufacturing a silicone hydrogel contact lens comprising:
- a) preparing a polymerizable composition comprising at least one acrylate-containing siloxane monomer represented by formula (I):
- where m is an integer from 3 to 10, n is an integer from 0 to 10, R1 is an alkyl group having 1 to 4 carbon atoms, R2 is hydrogen or a methyl group, and R3 is hydrogen or a methyl group,
- at least one hydrophilic vinyl-containing monomer, and at least one vinyl-containing cross-linking agent;
- b) polymerizing the polymerizable composition to form a polymeric lens body;
- and c) contacting the polymeric lens body with a washing liquid to remove unreacted or partially reacted components from the polymeric lens body,
- wherein the washing liquid and any other liquid used for washing the polymeric lens body are substantially free of volatile organic solvents;
- wherein the polymerizable composition has a molar ratio of total amount of hydrophilic vinyl-containing monomer to total amount of acrylate-containing siloxane monomer of from 5:1 to 30:1, respectively.
Dependencies are inferred from the claim text.