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US 9,216,194 B2Granted
Composite material for tissue repair
AssigneeSynthasome, Inc.
InventorAnthony Ratcliffe
Life of this patent
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Abstract
The present disclosure provides a biocompatible composite and method for its use in repairing tissue defects, including defects in cartilage. The biocompatible composite includes a fibrous polymeric component and a polymerizable agent, which is capable of forming the biocompatible composite in situ at the site of a tissue defect. In embodiments, the repair site at which the biocompatible composite is to be applied may be treated with a priming agent, permitting polymerization of the polymerizable agent to the tissue located at the repair site.
Claims7
A method comprising:
- identifying a tissue defect in cartilage, a ligament or a tendon for repair;
- applying a composite in combination with a polymerizable agent to the tissue defect, the composite including a fibrous polymeric component and a hydro gel formed in vitro on the fibrous polymeric component;
- and
- reacting the polymerizable agent with tissue at the site of the defect in the absence of a priming agent.
1 more element
An implant comprising:
- a composite including a porous fibrous material and a hydrogel composition formed in vitro on the fibrous polymeric component;
- and
- a polymerizable composition applied to the composite, the polymerizable composition including a polymerizable agent capable of covalently bonding to tissue in situ at a site of a tissue defect in cartilage, ligament, or tendon in the absence of a priming agent.
Dependencies are inferred from the claim text.