N-acetylcysteine amide (NAC amide) in the treatment of diseases and conditions associated with oxidative stress
OwnerGlenn A. Goldsteininventor
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Abstract
Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders, conditions and pathologies. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are administered alone, or in combination with other suitable agents, to reduce, prevent, or counteract oxidative stress and free radical oxidant formation and overproduction in cells and tissues, as well as to provide a new source of glutathione.
Claims25
A method for blocking or reducing hepatic toxicity of acetaminophen in a human subject, comprising administering to the human subject an effective dose of N-acetylcysteine amide (NAC Amide), or a pharmaceutically acceptable salt or ester thereof, thereby blocking or reducing hepatic toxicity of acetaminophen in the human subject.
A method of treating a human subject for hepatic toxicity of acetaminophen, comprising administering to the human subject an effective dose of N-acetylcysteine amide (NAC Amide), or a pharmaceutically acceptable salt or ester thereof, thereby treating the human subject in need of treatment for hepatic toxicity of acetaminophen.
A combination pharmaceutical composition comprising N-acetylcysteine amide (NAC Amide), and acetaminophen.
Dependencies are inferred from the claim text.