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US 9,205,133 B2Granted
Therapeutic for treating Clostridium difficile infection
AssigneeLondon School of Hygiene and Tropical Medicine
InventorsLisa Dawson, Brendan Wren
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AssigneeLondon School of Hygiene and Tropical Medicine
InventorsLisa Dawson, Brendan Wren
Estimating the term…
The invention relates to deoxyribonuclease for use in the treatment of a suspected or existing C. difficile infection; a pharmaceutical or veterinary composition or formulation comprising at least deoxyribonuclease for use in the treatment of a suspected or existing C. difficile infection; a combination therapeutic comprising at least deoxyribonuclease for use in the treatment of a suspected or existing C. difficile infection; a method of treating a mammal suspected of being infected with, or infected with, C. difficile comprising the use of at least deoxyribonuclease; a method of cleaning or sterilizing a material or product comprising the use of at least deoxyribonuclease; and a cleaning or sterilizing product impregnated with or containing at least deoxyribonuclease.
A method of treating Clostridium difficile biofilm formation in a mammal, comprising administering to said mammal an effective amount of a DNase I deoxyribonuclease or a functional fragment thereof, thereby degrading the Clostridium difficile biofilm.
Dependencies are inferred from the claim text.