Inositol hexakisphosphate analogs and uses thereof
AssigneeBoard of Regents, The University of Texas Systems
InventorsTor C. Savidge, Petril Urvil, Dhananjaya Nauduri, Numan Oezguen, Catherine Schein, Werner Braun
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Abstract
Provided herein are analog and derivative compounds of inositol hexakisphosphate effective to treat a Clostridium difficile infection and to neutralize the bacterial toxins produced by the same. In addition, methods of treating the C. difficile infection and for neutralizing its toxins with the compounds are provided.
Claims5
A method for neutralizing a Clostridium difficile bacterial toxin, comprising contacting the C. difficile bacterial toxin with an inositol hexakisphosphate analog having a chemical structure of Formula I:
- wherein R1, R2, R3, R4, R5, and R6 are —PS(OH)2.
Dependencies are inferred from the claim text.