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US 9,192,651 B2Granted
Modified polynucleotides for the production of secreted proteins
AssigneeModerna Therapeutics, Inc.
InventorsTirtha Chakraborty, Antonin de Fougerolles
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Abstract
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
Claims9
An isolated polynucleotide which is an mRNA, said mRNA comprising:
- a first region of linked nucleosides, said first region encoding SEQ ID NO:
- 2626 and said first region having at least 85% identity to SEQ ID NO:
- 15265.
Dependencies are inferred from the claim text.