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US 9,181,577 B2Granted
Treatment of chronic pelvic pain syndrome
AssigneeNorthwestern University
InventorsPraveen Thumbikat, Anthony J. Schaeffer, Joseph Done, David J. Klumpp, Charles Rudick
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Abstract
The present invention provides compositions and methods for detection, diagnosis, treatment and/or prevention of chronic pelvic pain syndrome. In particular, the present invention provides biomarkers of chronic pelvic pain syndrome (e.g., mast cell markers (e.g., tryptase)), and/or inhibition of mast cell function (e.g. inhibition of MCP-1 and/or MIP-1α) to treat or prevent chronic pelvic pain syndrome.
Claims5
A composition for the treatment of chronic pelvic pain syndrome (CPPS), comprising:
- a) a mast cell stabilizer;
- and
- b) a histamine receptor 1 antagonist and/or a histamine receptor 2 antagonist;
- wherein the composition is formulated for administration by a route other than inhalation.
1 more element
Dependencies are inferred from the claim text.