Inhibition of angiogenesis
AssigneeCornell Research Foundation, Inc.
InventorsMariana Lagos-Quintana, Shahin Rafii, Sai H. Chavala
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Abstract
The present invention relates to the microRNA miR-126 and to inhibitors of miR-126 that regulate angiogenesis. The present invention provides compositions and methods for the inhibition of miR-126 and for the inhibition of angiogenesis in vivo.
Claims23
A method of inhibiting angiogenesis in a subject in need thereof, the method comprising administering to the subject an effective amount of an inhibitor of miR-126, wherein miR-126 is set forth in SEQ ID. NO:
- 1 or SEQ ID. NO:
- 2.
A method of treating an eye disease associated with excessive blood vessel growth in a subject in need thereof, the method comprising administering to the subject an effective amount of an inhibitor of miR-126, wherein miR-126 is set forth in SEQ ID. NO:
- 1 or SEQ ID. NO:
- 2.
Dependencies are inferred from the claim text.