Method of applying a biological specimen to an analytic plate

A method of applying a biological sample to an analytic plate, comprising:

• applying a fluid composition to a surface of the analytic plate with an applicator to form a containment border extending from one edge of the analytic plate to an opposing edge thereof, the applicator being a pen or pen-like device having a body with a reservoir and an applicator end with a tip extending from the body, the fluid composition being positioned in the reservoir and comprising a polysiloxane, a siloxane, a silane, a silicone, a silicon fluid, or a combination thereof,
• wherein the fluid composition is applied to the surface of the analytic plate by appressing the tip of the applicator end to the surface of the analytic plate to cause the fluid composition to flow from the reservoir of the body, through the tip, and onto the surface of the analytic plate to form the containment border in a way that the containment border has a thickness of less than 0.0001 inches after drying;
• and
• applying the biological sample to the surface of analytic plate after the containment border has been applied to the analytic plate.