Recombinant adenovirus with enhanced therapeutic effect and pharmaceutical composition comprising said recombinant adenovirus
AssigneeIndustry-University Cooperation Foundation Hanyang University
InventorsChae-ok Yun, Joo-Hang Kim
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Abstract
Disclosed is a recombinant adenovirus with a protein containing a VSV-G epitope derived from vesicular stomatitis virus (VSV). Also, the present invention discloses a pharmaceutical composition comprising such a recombinant adenovirus and a pharmaceutically acceptable carrier. Further, the present invention discloses a recombinant plasmid capable of expressing the recombinant adenovirus and a host cell transformed with the recombinant adenovirus.
Claims4
A recombinant adenovirus wherein the construct is YCI-Ad-VSVG, wherein the recombinant adenovirus is capable of targeting and productively infecting a cancer cell.
Dependencies are inferred from the claim text.