Back to results
US 9,175,263 B2Granted
Methods and compositions for targeting progenitor cell lines
OwnerDavid Larocca, Paola Bignone +2inventors
InventorsDavid Larocca, Paola Bignone, Michael West, Evan Snyder
Life of this patent
Estimating the term…
Abstract
The invention provides methods, compositions and kits for the identification and enrichment of progenitor cell lines obtained from pluripotent stem cells.
Claims12
A peptide that binds to a progenitor cell wherein the peptide is selected from the group consisting of peptides comprising the following sequences:
- SWTYSYPNQNMD (SEQ ID NO:
- 1);
- DWTYSLPGLVEE (SEQ ID NO:
- 2);
- NWTWSMPTGNPA (SEQ ID NO:
- 3);
- GMTLRVLTN-YTE- (SEQ ID NO:
- 4);
- TLHVSENSWTYN (SEQ ID NO:
- 5);
- DWLWSFAPNVDT (SEQ ID NO:
- 6);
- TLSSQNPYMHKK (SEQ ID NO:
- 7);
- IDKQMMTSHKAI (SEQ ID NO:
- 8);
- QGMETQKLRMLK (SEQ ID NO:
- 9);
- GWYWETPLDMFN (SEQ ID NO:
- 10);
- GWVIDYDYYPMR (SEQ ID NO:
- 11);
- VTAENYQSFSVS (SEQ ID NO:
- 12);
- NNKMDDRMMMSIV (SEQ ID NO:
- 13);
- STGTDLHSNARI (SEQ ID NO:
- 14);
- YEFDNLLNRTLW (SEQ ID NO:
- 15);
- and EWTVNERTMWDL (SEQ ID NO:
- 16).
29 more elements
A composition comprising a progenitor cell and a peptide specifically bound to the progenitor cell, wherein the progenitor cell is the in vitro progeny of a pluripotent stem cell, and wherein the peptide has a length of 8-35 amino acids.
Dependencies are inferred from the claim text.