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US 9,175,043 B2Granted
Agents providing controls and standards for immuno-precipitation assays
AssigneeThe General Hospital Corporation
InventorsBradley E. Bernstein, Alon Goren
Life of this patent
Estimating the term…
Abstract
Control agents for immuno-precipitation assays, methods of using the control agents and kits comprising the control agents are provided.
Claims16
A polypeptide-oligonucleotide conjugate of the formula:
- A-L-N,
- wherein A is a polypeptide comprising 5 amino acids, L is a chemical linker, and N is an oligonucleotide comprising 10 nucleotides, wherein a sequence of nucleotides of N uniquely identifies an amino acid sequence and/or amino acid modification of A, and wherein A comprises an amino acid sequence derived from a histone protein selected from the group consisting of histone H1, H2A, H2AX, H2B, H3 and H4.
Dependencies are inferred from the claim text.