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US 9,175,042 B2Granted
Cyclosporin analogs
AssigneeAllergan, Inc.
InventorsMichael E. Garst, William Carling, David Scowen, Michael E. Stern, Christopher S. Schaumburg
Life of this patent
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Abstract
Disclosed herein are novel analogs of cyclosporin, pharmaceutical compositions containing them, and methods for their use in the treatment of dry eye and other conditions.
Claims1
A compound selected from the group consisting of:
- [(R)-(3-morpholin-4-yl-propylthio)-Sar]3 cyclosporin A;
- [(R)-(3-ethylisopropylamino-propylthio)-Sar]3 cyclosporin A;
- [(R)-(3-(4-methyl-piperazin-1-yl)-propylthio)-Sar]3 cyclosporin A;
- and pharmaceutically acceptable salts of any of said compounds.
1 more element
Dependencies are inferred from the claim text.