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AssigneeWockhardt Limited
InventorsBharat Trivedi, Prasad Deshpande, Ravikumar Tadiparthi, Sunil Gupta, Santosh Diwakar, Shivaji Pawar, Vijay Patil, Deepak Dekhane, Mahesh Patel, Satish Bhavsar, Amit Mishra, Manish Solanki, Mohammad Jafri, Sachin Bhagwat
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The invention relates to ketolide compounds of Formula (I) and their pharmaceutically acceptable salts, solvates, hydrates, polymorphs and stereoisomers having antimicrobial activity. The invention also provides pharmaceutical compositions containing the compounds of invention and methods of treating or preventing microbial infections with the compounds of invention, wherein, T is —C*H(R1)—P-Q; R1 is hydrogen; unsubstituted or substituted lower alkyl, cycloalkyl or aryl; P is heteroaryl ring; Q is unsubstituted or substituted aryl or heteroaryl ring; and P is attached to Q via carbon-carbon link; and R3 is hydrogen or fluorine, With the provision that when R1 is hydrogen, R3 is fluorine.
A compound of formula (I) or a pharmaceutically acceptable salt, solvate, hydrate, or a polymorph thereof,
A compound, which is:
A compound which is:
Dependencies are inferred from the claim text.