Crystalline forms of 6-(1H-imidazol-1-yl)-2-phenylquinazoline

A crystalline form of 6-(1H-imidazol-1-yl)-2-phenylquinazoline (L)-tartrate, form D, having one or more of the following features:

• i) an X-ray powder diffraction spectrum (XRPD) as shown in FIG. 41 and/or comprising the main peaks at diffraction angles (2θ°) 9.60, 9.98, 11.47, 12.44, 17.37, 18.75, 18.99, 19.21, and 19.56;
• ii) a DSC thermogram with endothermic effect at about 189° C., as shown in FIG. 42;
• and
• iii) an FT-IR spectrum as shown in FIG. 43.

A crystalline form of 6-(1H-imidazol-1-yl)-2-phenylquinazoline maleate, comprising a triclinic system with cell parameters a=8.9412 (5) Å, b=9.8081 (5) Å, c=10.5922 (6) Å, α:

• 90.517° (4), β=101.969° (5), γ=99.132° (4), V=896.34 (8) Å3, space group P-1, having one or more of the following features:
• i) an X-ray powder diffraction spectrum (XRPD) as shown in FIG. 47 and/or comprising the main peaks at diffraction angles (2θ°) 8.77, 9.31, 12.05, 12.38, 12.75, 15.89, 18.49, 20.05, 25.91, and 27.29;
• ii) a DSC thermogram with an endothermic effect with onset at about 156° C. and a second endothermic effect with onset at about 243° C., as shown in FIG. 48;
• and
• iii) an FT-IR spectrum as shown in FIG. 49.

A hemihydrated crystalline form of 6-(1H-imidazol-1-yl)-2-phenylquinazoline maleate, having one or more of the following features:

• i) an X-ray powder diffraction spectrum (XRPD) as shown in FIG. 50 and/or comprising the main peaks at diffraction angles (2θ°) 8.77, 9.31, 12.05, 12.38, 12.75, 15.89, 18.49, 20.05, 25.91, and 27.29;
• ii) a DSC thermogram as shown in FIG. 51, which shows an endothermic event with peak at about 83° C., and an endothermic event with onset at about 153° C. and an endothermic event with onset at about 228° C.;
• and
• iii) an FT-IR spectrum as shown in FIG. 52.

A crystalline form of 6-(1H-imidazol-1-yl)-2-phenylquinazoline fumarate, comprising a monoclinic system with cell parameters a=10.7980 (8) Å, b=11.6643 (7) Å, c=13.0888 (11) Å, α:

• 90°, β=106.842° (8), γ=90°, V=1577.8 (2) Å3, space group P21/c, having one or more of the following features:
• i) an X-ray powder diffraction spectrum (XRPD) as shown in FIG. 44 and/or comprising the main peaks at diffraction angles (2θ°) 15.22, 16.85, 17.54, 17.96, 22.64, 25.90, and 26.72;
• ii) a DSC thermogram with endothermic effect with onset at about 199° C., endothermic effect with onset at about 200° C., and a third endothermic effect with onset at about 240° C., as shown in FIG. 45;
• and
• iii) an FT-IR spectrum as shown in FIG. 46.