c-Met modulators and methods of use

A process for preparing a compound of formula XXIb:

• comprising reaction of a compound of Formula XXIIb, with a compound of Formula XXIIIb:
• wherein:
• J is ═C(H)—;
• R2 is selected from —H, halogen, trihalomethyl, —CN, —NO2, —NH2, —OR3, —NR3R3, —S(O)0-2R3, —SO2NR3R3, —CO2R3, —C(O)NR3R3, —N(R3)SO2R3, —N(R3)C(O)R3, —N(R3)CO2R3, —C(O)R3, and optionally substituted C1-6alkyl;
• each R3 is independently selected from —H, —Si(R5)(R5)R5, optionally substituted lower alkyl, optionally substituted aryl, optionally substituted arylalkyl, and optionally substituted heteroarylalkyl;
• two R3, together with the nitrogen to which they are attached, form a four- to seven-membered heteroalicyclic, said four- to seven-membered heteroalicyclic optionally containing one additional heteroatom;
• when one said additional heteroatom is a nitrogen, then said nitrogen is optionally substituted with a group selected from —H, trihalomethyl, —SO2R5, —SO2NR5R5, —CO2R5, —C(O)NR5R5, —C(O)R5, and optionally substituted lower alkyl;
• each R20 is independently selected from —H, halogen, trihalomethyl, —CN, —NO2, —NH2, —OR3, —NR3R3, —S(O)0-2R3, —SO2NR3R3, —CO2R3, —C(O)NR3R3, —N(R3)SO2R3, —N(R3)C(O)R3, —N(R3)CO2R3, —C(O)R3, optionally substituted C1-6alkyl, optionally substituted aryl, optionally substituted aryl C1-6alkyl, optionally substituted heterocyclyl, and optionally substituted heterocyclyl C1-6alkyl;
• two of R20, together with the atom or atoms to which they are attached, combine to form an optionally substituted three- to seven-membered heteroalicyclic;
• R50 is lower alkyl;
• and
• P1 is selected from chlorine, bromine, a toluene sulfonate, and trifluoromethansulfonate.